SHELTERS LISTED by CITY
- Aiken
- Aiken SPCA
- 401 Wire Rd, Aiken, SC 803-648-6863
- Anderson
- Anderson County Humane Society
- 1621 N Main St # 105, Anderson, SC 864-225-9855
- Anderson
- Anderson Animal Shelter
- 615 Bypass 28 S, Anderson, SC 864-260-4154
- Beaufort
- Beaufort County Animal Shelter
- US Hwy 21, Beaufort, SC 843-846-3904
- Bennettsville
- Bennettsville Animal Shelter
- 110 Huckabee St, Bennettsville, SC 843-479-7550
- Burton
- Beaufort Humane Association
- PO Box 4326, Burton, SC (843) 522-4499 Email
- Camden
- Walter M. Crowe Animal Shelter
- 460 Fair St, Camden, SC (803) 425-6016
- Charleston
- John Ancrum SPCA
- 3861 Leeds Ave, Charleston, SC 843-747-4849
- Charleston
- Pet Helpers
- 1430 Folly Rd, Charleston, SC 843-795-1110 Email
- Chester
- Chester County Animal Shelter
- 2714 Dawson Dr, Chester, SC (803) 385-6341
- Columbia
- City of Columbia Animal Shelter
- 127 Humane Ln, Columbia, SC 803-776-7387
- Columbia
- Humane SPCA
- 121 Humane Ln, Columbia, SC 803-783-1267
- Columbia
- Humane Society Spay-Neuter Program
- 121 Humane Ln, Columbia, SC 803-776-8084
- Florence
- Florence Humane Society
- 1007 Stockade Dr, Florence, SC 843-669-2921 Email
- Fort Mill
- Humane Society of York County
- 2036 Carolina Pl, Fort Mill, SC (803) 802-0902 Spay/Neuter 802-0925
- Gaffney
- Cherokee County Animal Shelter
- 300 Yale St, Gaffney, SC 864-487-2758
- Georgetown
- St. Frances Humane Society
- 125 Ridge Rd, Georgetown, SC 843-546-0780 Email
- Goose Creek
- Berkeley County P.A.W.S.
- P.O. Box 903, Goose Creek, SC (843) 688-4414 (Moncks Corner)
(Charleston) (843) 207-PAWS Voice Mail- Greenville
- Greenville Humane Society
- 328 Furman Hall Rd, Greenville, SC 864-242-3626
- Hopkins
- Animal Protection League
- 6080 Old Leesburg Rd, Hopkins, SC 803-783-2119
- Hilton Head
- Animal Welfare League
- Shelter Cove Mall, Hilton Head, SC 843-842-9927
- Hilton Head
- Hilton Head Humane Association
- PO Box 21790, Hilton Head, SC 843-681-8686 Email
- Lancaster
- Lancaster County Humane Society
- Lancaster, SC 803-283-1833
- Liberty
- Foothill's Humane Society
- 500 Five Forks Rd, Liberty, SC 864-843-9693
- Myrtle Beach
- Grand Strand Humane Society
- 10th Avenue Ext N, Myrtle Beach, SC 843-448-9151
- North Myrtle Beach
- Humane Society of North Myrtle Beach
- 409 Bay St, North Myrtle Beach, SC 843-249-4948 Email
- Orangeburg
- Orangeburg Animal Shelter
- 2572 Saint Matthews Rd NE, Orangeburg, SC 803-534-0045
- Orangeburg
- Orangeburg SPCA
- 125 Ruf Rd, Orangeburg, SC 803-536-3918
- Rock Hill
- Animal Outreach of York County
- 1938 Oak Pond Rd, Rock Hill, SC 29730 (803) 324-0859 Email
- Simpsonville
- Concerned Citizens For Animals
- PO Box 1332, Simpsonville, SC 29681 (864) 243-4222 Email
- Spartanburg
- Spartanburg Animal Control
- 145 W Broad St, Spartanburg, SC 29306 (864) 582-1558
- Spartanburg
- Spartanburg Humane Society
- 150 Dexter Road, Spartanburg, SC (864) 583-4805
- Summerville
- Frances R. Willis SPCA
- 136 Four Paws Ln, Summerville, SC (843) 871-3820 Email
- Sumter
- SPCA Humane Organization
- 1140 S Guignard Dr, Sumter, SC 803-773-9292
- Union
- Union County Animal Shelter
- Hwy 176, Union, SC 864-429-1677
- Walhalla
- Oconee County Humane Society
- 321 Camp Rd, Walhalla, SC 864-638-8798
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